MM-001: A Phase 1 Study of Anti-CD38 CAR-T Therapy in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)
Principle Investigator: Todd Roberts, MD
Eligibility Criteria:
Population 1:
Adults with RRMM after receiving at least the following:
- Lenalidomide (Revlimid®)
- Pomalidomide (Pomalyst®)
- Bortezomib (Velcade®)
- Carfilzomib (Kyprolis®)
- Daratumumab (Darzalex®)
Or
Population 2:
Adults with RRMM within 1 year of receiving Autologous Stem Cell Transplant and:
- Measurable Disease
- No myeloma involvement of the central nervous system,
- brain metastasis, or spinal cord compression
- No active plasma cell leukemia
- Good performance status
Contact Information:
Alexandra Milhaupt BSN, RN
Immunotherapy Nurse Coordinator
Office of Therapeutic Development
Phone: (401) 456-2526
alexandra.milhaupt@CharterCARE.org
CEA-001: A Phase 1 Study of Anti-CEA CAR-T Therapy for Patients with Pancreatic Cancer Liver Metastases
Principle Investigator: Steven Katz, MD, FACS
Eligibility Criteria:
- Tumor must be CEA-expressing (CEA >10)
- Liver metastases must be documented
- Failed at least one line of standard chemotherapy
- Good performance status
Contact Information:
Gabrielle Masse BSN, RN
Immunotherapy Clinical Research Nurse
Office of Therapeutic Development
Phone: 401-456-2659
gabrielle.masse@chartercare.org
RWMC-IPC 001 Peritoneal Carcinomatosis or Malignant Ascites (RWH 340-74)
Phase 1 Trial of Anti-CEA CAR-T Cell Intraperitoneal Infusions for Treatment in Patients with CEA+-Expressing Adenocarcinoma Peritoneal Metastases or Malignant Ascites. (RWH 340-74)
Contact Information
(All team members listed below are located at Roger Williams Medical Center, 825 Chalkstone Avenue, Providence, RI 02908)
Ashley Moody, BSN, RN (Immunotherapy Research Nurse Manager)
401-456-2268
Email: alarkin@chartercare.org
Alexandra Milhaupt, BSN, RN (Immunotherapy Nurse)
401-456-2526
Email: alexandra.milhaupt@chartercare.org
Catherine Conley, BS (Immunotherapy Research Data Collection Manager)
401-456-2397
Email: Catherine.conley@chartercare.org